The Fountain of Youth May be Found In Sirtuins PDF Print E-mail
Post by Jo Carey   
Monday, 01 December 2008 00:45
fountain, youth
No, a Sirtuin is not from the planet Sirtuis. It is a protein that is involved in the aging process. David A. Sinclair, a Harvard Medical School professor and co-founder of the Cambridge biotechnology company Sirtris Pharmaceutials, Inc., explains that the proteins help to maintain a youthful pattern of gene expression.
This pattern is maintained by making sure that the genes that are supposed to be "off" remain turned off. The same protein also repairs DNA damage as we age.

Sinclair says, “The critical protein controls both which genes are off and on as well as DNA repair; it's used for both processes, and that's the catch.” He explains that the aging process damages chromosomes and the SIR1 proteins can't keep up, causing gene activity to to go awry which causes the aging process.

The good news is that previous studies have found that resveratrol, a chemical found in red wine, the crust of peanuts and walnuts, grapes, peanut butter, pistachios and other foods, helps to activate SIRT1 protein.

These studies so far have been on mice so it is too soon to start taking drugs containing resveratrol. So, in the meantime, have a glass of red wine while you're waiting on the Fountan of Youth and enjoy!


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